This study purposes to examine the relationship between key audit matters and the value relevance of information. The study also investigates moderating role of audit committee expertise on the relationship between key audit matters and the value relevance of information of the listed in The Stock Exchange of Thailand (SET) in 2020. In this study, key audit matters is measured by number of key audit matters that the auditor states in auditor report, value relevance is measured by regressing stock prices on earning and book values following the Ohlson’s Model (1995) and audit committee expertise is measured by proportion of audit committee members with financial and account expertise to the total number of audit committee members. The result shows that key audit matters has no relationship between key audit matters and firm’s price. This implied that investors do not value key audit matters information for decision making. Moreover, the result reveal that audit committee expertise has no effects on the relationship between key audit matters and firm’s price, suggesting that number of audit committee expertise does not moderate on value of key audit matters information for decision making of investors.