Citrus reticulate Blanco peels are the main by-product of the industrial beverage of fruit processing which are rich in bioactive compounds. The objectives of this research were to increase the value of bioactive compounds from Citrus reticulate Blanco peels were consist of essential oil, pectin and total phenolic by microwave assisted extraction. The result found that microwave power at 450-600 watts was suitable for the extraction essential oils using microwave techniques with high quality of the essential oil and quick time of extraction. The highest pectin yield of 17.67% from Citrus reticulate Blanco peels was obtained at microwave power of 450 W, irradiation time of 75 s., soil-liquid ratio of 1:42.5 g/ml and pH of 1. The highest yield of total phenolic (35.08 mg/g of raw material) was received at microwave power of 340 W, irradiation time of 65 s., soil-liquid ratio of 1:35 g/ml. This research can be used to develop the process of extracting bioactive substances from tangerine peels for use in cosmetics or dietary supplements that are not harmful to consumers which is useful in increasing income and reducing waste disposal in the juice industry